State directory

Home health agencies in South Carolina

Quick answer

As of the CMS Care Compare July 2026 release, 68 Medicare-certified home health agencies have offices in South Carolina. 64 have a CMS quality-of-patient-care star rating, and 39 are rated 4 stars or higher. 5 share the highest rating here, 5 stars, including Amedisys Home Health Care, Amedisys Home Health of Beaufort and Amedisys Home Health of Conway (first three alphabetically). They are listed across 35 cities.

Source: CMS Care Compare · Data release: July 2026 · Updated

Every list is ordered by CMS quality star rating, ties alphabetical, unrated last. No agency pays to be listed or ranked. Methodology · Ownership disclosure

Largest cities

All cities with 3 or more agencies (8)

Agencies in smaller cities

33 agencies in 27 cities with fewer than 3 agency offices, combined and ordered by the same rule. Cities: Aiken, Anderson, Camden, Cheraw, Chester, Clinton, Conway, Gaffney, Georgetown, Greenwood, Hardeeville, Irmo, Kingstree, Ladys Island, Lancaster, Lexington, Lugoff, Murrells Inlet, Newberry, North Augusta, North Myrtle Beach, Orangeburg, Simpsonville, Spartanburg, Sumter, Walterboro, West Columbia.

  1. Rank 1

    Amedisys Home Health Care

    5 out of 5 · CMS stars
    127 E Mill Street, Kingstree, SC 29556(843) 355-5103
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1994 · CCN 427068CMS profile on Care Compare for Amedisys Home Health Care
  2. Rank 2

    Amedisys Home Health of Beaufort

    5 out of 5 · CMS stars
    35 Professional Village Circle, Ladys Island, SC 29907(843) 379-2320
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    Proprietary · Medicare-certified since 2003 · CCN 427304CMS profile on Care Compare for Amedisys Home Health of Beaufort
  3. Rank 3

    Amedisys Home Health of Conway

    5 out of 5 · CMS stars
    308 Elm Street, Conway, SC 29526(843) 507-8058
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1999 · CCN 427112CMS profile on Care Compare for Amedisys Home Health of Conway
  4. Rank 4

    Neighbors Care Home Health Agency, An Amedisys Co

    5 out of 5 · CMS stars
    1645 Ja Cochran Bypass Suite 1, Chester, SC 29706(866) 327-3205
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    Proprietary · Medicare-certified since 1993 · CCN 427063CMS profile on Care Compare for Neighbors Care Home Health Agency, An Amedisys Co
  5. Rank 5

    Nhc Homecare Murrells Inlet

    5 out of 5 · CMS stars
    11947 Grandhaven Drive, Murrells Inlet, SC 29576(843) 945-9850
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    Proprietary · Medicare-certified since 2014 · CCN 427124CMS profile on Care Compare for Nhc Homecare Murrells Inlet
  6. Rank 6

    Amedisys Home Health of Camden

    4.5 out of 5 · CMS stars
    2209 West Delkab Street, Camden, SC 29020(803) 713-9774
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1985 · CCN 427036CMS profile on Care Compare for Amedisys Home Health of Camden
  7. Rank 7

    Amedisys Home Health of Clinton

    4.5 out of 5 · CMS stars
    210 Physicians Park Dr, Ste U, Clinton, SC 29325(225) 299-3218
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 2003 · CCN 427116CMS profile on Care Compare for Amedisys Home Health of Clinton
  8. Rank 8

    Amedisys Home Health of Georgetown

    4.5 out of 5 · CMS stars
    2503 Highmarket Street, Georgetown, SC 29440(843) 546-1730
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1993 · CCN 427065CMS profile on Care Compare for Amedisys Home Health of Georgetown
  9. Rank 9

    Amedisys Home Health of Lexington

    4.5 out of 5 · CMS stars
    714 Southlake Drive Suite 250, Lexington, SC 29072(803) 720-5244
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1987 · CCN 427039CMS profile on Care Compare for Amedisys Home Health of Lexington
  10. Rank 10

    Centerwell Home Health

    4.5 out of 5 · CMS stars
    206 Chesnee Highway, Suite H, Gaffney, SC 29341(864) 488-0898
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 2007 · CCN 427117CMS profile on Care Compare for Centerwell Home Health
  11. Rank 11

    Centerwell Home Health

    4.5 out of 5 · CMS stars
    1704 E Greenville Street, Suite 2d, Anderson, SC 29621(864) 932-4970
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1971 · CCN 427846CMS profile on Care Compare for Centerwell Home Health
  12. Rank 12

    Centerwell Home Health

    4.5 out of 5 · CMS stars
    185 Executive Dr., Newberry, SC 29108(803) 276-0273
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1973 · CCN 427850CMS profile on Care Compare for Centerwell Home Health
  13. Rank 13

    Centerwell Home Health

    4.5 out of 5 · CMS stars
    415 E Robertson Blvd, Walterboro, SC 29488(843) 542-9540
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1974 · CCN 427856CMS profile on Care Compare for Centerwell Home Health
  14. Rank 14

    Nhc Homecare Laurens

    4.5 out of 5 · CMS stars
    700 Plaza Circle, Suite O, Clinton, SC 29325(864) 833-2368
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    Proprietary · Medicare-certified since 1996 · CCN 427079CMS profile on Care Compare for Nhc Homecare Laurens
  15. Rank 15

    Prisma Health Tuomey

    4.5 out of 5 · CMS stars
    500 Pinewood Road Suite 2, Sumter, SC 29154(803) 296-2548
    • Skilled nursing
    • Physical therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Non-Profit · Medicare-certified since 1996 · CCN 427078CMS profile on Care Compare for Prisma Health Tuomey
  16. Rank 16

    Aveanna Home Health

    4 out of 5 · CMS stars
    300 New River Pkwy Ste 7, Hardeeville, SC 29927(843) 208-3660
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    Proprietary · Medicare-certified since 2023 · CCN 427863CMS profile on Care Compare for Aveanna Home Health
  17. Rank 17

    Musc Health at Home by Bayada-Conway

    4 out of 5 · CMS stars
    1300 South Carolina Highway 544, Conway, SC 29526(973) 909-5159
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
  18. Rank 18

    Nhc Homecare Aiken

    4 out of 5 · CMS stars
    233 Pendleton St. Nw, Aiken, SC 29801(803) 643-1701
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Medical social services
    Proprietary · Medicare-certified since 1996 · CCN 427077CMS profile on Care Compare for Nhc Homecare Aiken
  19. Rank 19

    Nhc Homecare Greenwood

    4 out of 5 · CMS stars
    452 Cambridge Avenue, Greenwood, SC 29646(864) 229-9888
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Home health aide
    Proprietary · Medicare-certified since 1995 · CCN 427075CMS profile on Care Compare for Nhc Homecare Greenwood
  20. Rank 20

    Adoration Home Health

    3.5 out of 5 · CMS stars
    901 Meeting St, Lancaster, SC 29720(803) 286-1472
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1985 · CCN 427034CMS profile on Care Compare for Adoration Home Health
  21. Rank 21

    Home Health Services of Self Regional Healthcare

    3.5 out of 5 · CMS stars
    1325 Spring Street, Greenwood, SC 29646(864) 725-7600
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1980 · CCN 427018CMS profile on Care Compare for Home Health Services of Self Regional Healthcare
  22. Rank 22

    Musc Health at Home Kershaw

    3.5 out of 5 · CMS stars
    1165 Highway 1 South, Suite 400, Lugoff, SC 29078(803) 425-1182
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1991 · CCN 427046CMS profile on Care Compare for Musc Health at Home Kershaw
  23. Rank 23

    St Francis Hospital Home Care

    3.5 out of 5 · CMS stars
    1836 West Georgia Road, Simpsonville, SC 29680(864) 233-5300
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Non-Profit · Medicare-certified since 1991 · CCN 427049CMS profile on Care Compare for St Francis Hospital Home Care
  24. Rank 24

    Suncrest Home Health

    3.5 out of 5 · CMS stars
    227 Market Street, Cheraw, SC 29520(843) 537-3020
    • Skilled nursing
    • Physical therapy
    Proprietary · Medicare-certified since 1981 · CCN 427020CMS profile on Care Compare for Suncrest Home Health
  25. Rank 25

    Trinity Home Health of Aiken

    3.5 out of 5 · CMS stars
    690 Medical Park Dr Suite 400, Aiken, SC 29803(803) 641-8220
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 2009 · CCN 427119CMS profile on Care Compare for Trinity Home Health of Aiken
  26. Rank 26

    Anmed Home Health Agency

    3 out of 5 · CMS stars
    1926 McConnell Springs Rd Po Box 195, Anderson, SC 29622(864) 512-6410
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1985 · CCN 427032CMS profile on Care Compare for Anmed Home Health Agency
  27. Rank 27

    Medical Services of America Home Health

    3 out of 5 · CMS stars
    2 Palmetto Wood Pkwy Suite 201, Irmo, SC 29063(803) 561-7680
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1979 · CCN 427010CMS profile on Care Compare for Medical Services of America Home Health
  28. Rank 28

    Nhc Home Care Midlands

    3 out of 5 · CMS stars
    3227 Sunset Blvd, Suite F101, West Columbia, SC 29169(803) 939-0266
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    Proprietary · Medicare-certified since 1997 · CCN 427302CMS profile on Care Compare for Nhc Home Care Midlands
  29. Rank 29

    Spartanburg Regional Home Health

    3 out of 5 · CMS stars
    120 Heywood Ave, Spartanburg, SC 29302(864) 560-3900
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Government Operated · Medicare-certified since 1981 · CCN 427024CMS profile on Care Compare for Spartanburg Regional Home Health
  30. Rank 30

    University Home Health

    3 out of 5 · CMS stars
    106b East Martintown Rd, North Augusta, SC 29841(803) 278-0770
    • Skilled nursing
    • Physical therapy
    • Occupational therapy
    • Speech-language pathology
    • Medical social services
    • Home health aide
    Proprietary · Medicare-certified since 1981 · CCN 427300CMS profile on Care Compare for University Home Health
  31. Rank 31

    Grove Park Pharmacy Home Care, LLC

    2.5 out of 5 · CMS stars
    1353 Grove Park Drive, Orangeburg, SC 29115(803) 536-6644
    • Skilled nursing
    • Physical therapy
    • Home health aide
    Proprietary · Medicare-certified since 2021 · CCN 427861CMS profile on Care Compare for Grove Park Pharmacy Home Care, LLC
  32. Rank 32

    Home Care of Trmc

    Not rated: too few patients for CMS to report
    1175 Cook Road Suite 325, Orangeburg, SC 29118(803) 533-2600
      Proprietary · Medicare-certified since 1997 · CCN 427110CMS profile on Care Compare for Home Care of Trmc
    • Rank 33

      Liberty Home Care, LLC

      Not rated: too few patients for CMS to report
      1019 Highway 17 S, Unit 124, North Myrtle Beach, SC 29582(843) 839-2273
      • Skilled nursing
      • Physical therapy
      • Occupational therapy
      • Medical social services
      • Home health aide
      Proprietary · Medicare-certified since 2010 · CCN 427121CMS profile on Care Compare for Liberty Home Care, LLC

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    Quick facts: 68 Medicare-certified home health agencies in South Carolina, by city, ranked by CMS quality star rating. CMS Care Compare, July 2026.